Ramazzini; Blog on work and health by Annet Lenderink


Working night shifts may be bad for the heart

This study in Austria among 30 healthy physicians was performed to evaluate the effects of a 24 h (h) physicians on-call duty (OCD) (‘night shift’) on 24 h electrocardiogram (ECG), heart rate variability, blood pressure (BP), and various biochemical serum and urine ‘stress markers’ compared with a ‘regular’ day at work. Twenty-four hours ECG showed a higher rate of ventricular premature beats (VPB) during early morning hours.  During OCD, BP monitoring revealed a greater diastolic BP throughout 24 h as well as during night-time and a higher rate of systolic BP during sleep time. Tumour necrosis factor alpha concentrations increased significantly during night shift and urinary noradrenaline excretion was greater during OCD when compared with control day. The researchers conclude that there is an association of OCD with an increased risk profile for cardiovascular disease.

Arrhythmias and increased neuro-endocrine stress response during physicians’ night shifts: a randomized cross-over trial
Markus Rauchenzauner, Florian Ernst, Florian Hintringer, Hanno Ulmer, Christoph F. Ebenbichler, Marie-Therese Kasseroler and Michael Joannidis
European Heart Journal 2009 30(21):2606-2613; doi:10.1093/eurheartj/ehp268 online publish-ahead-of-print 14 July 2009

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Filed under: cardio vascular, Occupational medicine, Psychosocial exposure, , ,

Risk of metabolic syndrome is closely related to working night shifts

The aim of this study from Italy was to assess whether a causal relationship exists between night-shift work and the development of metabolic syndrome (MS). Male and female nurses performing night shifts, free from any component of MS at baseline, were evaluated annually during a 4-year follow-up and compared to day-shift workers. The annual rate of incidence of MS was 2.9% in night-shift workers, significantly different from 0.5% in daytime workers. Among selected variables (age, gender, smoking, alcohol intake, familiar history, physical activity, and work schedule) the only predictors of occurrence of MS were sedentariness (hazard ratio (HR) 2.92; 95% CI 1.64 to 5.18; p = 0.017), and night-shift work (HR 5.10; 95% CI 2.15 to 12.11; p<0.001). The researchers conclude that the risk of developing MS is strongly associated with night-shift work in nurses.

Incidence of metabolic syndrome among night-shift healthcare workers
Pietroiusti, A, Neri, A, Somma, G, Coppeta, L, Iavicoli, I, Bergamaschi, A, Magrini, A
Occup Environ Med 2010;67:54-57 doi:10.1136/oem.2009.046797 Read the rest of this entry »

Filed under: cardio vascular, ,


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Annet Lenderink

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Diepenveen, Netherlands

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